# Sepsis Data Normalization and Merging

## Author: Cory H. White  

### Overview

This project directory contains data, scripts, and output from the cytokine normalization portion of the analysis for the accompanying manuscript.  Here is a brief description of each subdirectory within this project directory:  

* `./bin/`: this subdirectory contains all of the R code used for the analyses presented in the manuscript  
* `./data/`: this subdirectory contains input and output data used for the analyses  

### R version used

The code was developed for this manuscript using *R v4.0.2*.  No additional libraries were utilized:

### Running the code

To run the code for this project, make sure you are in the `./bin/` folder. To run the code that performs normalization, enter the command:

`Rscript Normalize_Cytokines.r`
`Rscript MergeData.r`

Input data for this code is present in the data directory and named:
`Patient 1 to 27-millipore kit.csv`
`RandD_1.csv`
`RandD_2.csv`

This will produce several files, two of which are used for the multiomics integration analyses for cytokines.  These files are as follows:

`lg2_Normalized_Cytokines_RandD_Merged.csv`
`lg2_Normalized_Cytokines_Millipore.csv`
